Stem Cell Factor (SCF) is a critical factor in the maintenance and expansion of hematopoietic stem cells (HSCs) in the bone marrow microenvironment. Key myeloid progenitor differentiation factor for a variety of myeloid cells such as megakaryocytes, basophils, neutrophils, and monocytes, Stem Cell Factor is also a primary growth and activation factor for mast cells and eosinophils.
Recombinant SCF is a highly pure 18.5 kDa monomer, animal origin-free (AOF) and carrier-protein-free (CF). Qkine has optimised the SCF manufacture process to produce a highly bioactive protein with excellent lot-to-lot consistency for enhanced experimental reproducibility.
- High purity human protein (Uniprot number: P21583)
- >98%, by SDS-PAGE quantitative densitometry
- Source: Expressed in E. coli
- Size in 18.5 kDa monomer
- Animal origin-free (AOF) and carrier protein-free
- Manufactured in Cambridge, UK
- Lyophilised from Acetonitrile/TFA
- Resuspend in water at >100µg/mL, prepare single-use aliquots, add carrier protein if desired, and store frozen at -20°C or -80°C